دانلود کتاب GI Microbiota and Regulation of the Immune System

Gary B. Huffnagle, PhD, is a Professor of Internal Medicine (PulmonaryDiseases) and Microbiology and Immunology at the University of Michigan MedicalSchool. He holds a BS in microbiology from Pennsylvania State University and aPhD in immunology from the University of Texas Southwestern Medical School.In addition to conducting research, he teaches undergraduate and graduate classesin eukaryotic microbiology, microbial symbiosis and experimental immunologyat the University of Michigan. Dr. Huffnagle’s research focuses on the regulationof pulmonary immunity to infectious agents and allergens. In the past 5 years, hisattention has turned to the role of the indigenous microbiota in immune systemfunctioning, as well as the role of probiotics in animal and human health. He hasbeen awarded research grants from the National Heart, Lung and Blood Institute(NHL BI), National Institute of Allergy and Infectious Diseases (NIAID), the FrancisFamilies Foundation and the Burroughs-Wellcome Fund. Dr. Huffnagle serves orhas served on editorial boards for the American Society for Microbiology (ASM)and the American Association of Immunologists (AAI), as well as on advisory andreview panels for the National Institutes of Health (NIH).Mairi C. Nove rr, PhD, is an Assistant Professor of Immunology andMicrobiology at Wayne State University Medical School. She earned a BA in biologyfrom Kalamazoo College in 1996 and a PhD in microbiology and immunologyfrom the University of Michigan in 2002. Dr. Noverr’s current research focuses oninvestigating mechanisms of immunomodulation by the opportunistic yeast Candidaalbicans during host-pathogen interactions and how interactions with other membersof the microbiota influence these interactions. Her laboratory is investigatingsignaling compounds called oxylipins that are produced by both Candida and thehost, which can influence the microbiology of the fungus and the activity of hostimmune system cells. Projects in the laboratory include molecular characterizationof the fungal oxylipin biosynthetic pathways and determining the effects of oxylipinsduring Candida pathogenesis, in modulating host immune cell function, andduring fungal-bacterial interactions. She has been awarded research funding fromthe Francis Families Foundation.