دانلود کتاب Erythropoietin: Blood, Brain and Beyond

The use of Epo in medical practice is increasing constantly. It has revolutionized how we think of blood transfusion in medicine and surgery. Moreover, it has become widely known to scientists, physicians, biotech and pharmaceutical executives and the general public. Additionally, the past ten years have seen important advances in our knowledge and understanding of its action both within and outside of the hematopoietic system. Until now, there has been no single source that contains up-to-date information on Epo addressing the array of subjects that this book presents. The book covers all aspects from developmental biology to specific topics such as medical applications of recombinant Epo, receptor biology, mechanisms of Epo activity, structure/activity relationship, disease states and important actions on non-hematopoietic organs and tissues, including the central nervous system, heart, gastrointestinal tract, reproductive organs and endothelium.Content: Chapter 1 Introduction and History (pages 1–8): Chapter 2 Developmental Biology of Erythropoiesis and Erythropoietin Production (pages 9–23): Chapter 3 Regulation of the Erythropoietin Gene: A Paradigm for Hypoxia?dependent Genes (pages 25–41): Chapter 4 Physiology and Metabolism of Erythropoietin (pages 43–53): Chapter 5 Biochemistry and Protein Structure (pages 55–71): Chapter 6 Receptor Biology and Signal Transduction (pages 73–100): Chapter 7 Clinical Disorders of Erythropoietin and its Receptor (pages 101–115): Chapter 8 Recombinant Erythropoietin and the Treatment of Anemia (pages 117–154): Chapter 9 Functions of Erythropoietin Outside of Hematopoiesis (pages 155–182): Chapter 10 Erythropoietin and Sport (pages 183–197): Chapter 11 The Future of Erythropoietin (pages 199–215):